* Xanax contains a boxed warning about the risk of significant harm or Demise if taken with opioids. A boxed warning is considered the most major warning from your FDA. For more information, see the “Xanax precautions” section down below.Digoxin. Digoxin (Lanoxin) is a coronary heart medication. Having Xanax with digoxin might bring about digox… Read More